Sanofi’s closely-watched SERD amcenestrant could succeed in earlier lines of metastatic breast cancer despite disappointment in an advanced disease study which has knocked the candidate from its pole position.
Sanofi's SERD Candidate Founders In Advanced Breast Cancer
But Hope Remains For Earlier Setting
The French major’s amcenestrant has missed its primary endpoint in a Phase II study of advanced breast cancer patients but could still have potential in earlier adjuvant disease.
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The study’s failure in the overall MDD population was not a surprise, but solriamfetol’s efficacy in MDD with EDS provided a rationale for testing it in that subpopulation.