CAR-T has revolutionized the treatment options for blood cancers but its application for solid tumors has fallen short. The German biotech hopes that by combining a CAR-T cell therapy with an mRNA vaccine could be a gamechanger.
Building on the success of its Pfizer Inc.-partnered COVID-19 vaccine Comirnaty, BioNTech SE has presented a promising update on its first CAR-T candidate, both alone and in combination with an mRNA vaccine, as a potential treatment for certain solid tumors.
The German biotech has presented initial data from its ongoing first-in-human Phase I/II trial at the American Association for Cancer Research (AACR) congress in New Orleans evaluating BNT211 in patients with advanced solid tumors
Mid-sized Japanese pharma firm to acquire tobacco giant’s pharma operations and take private the listed Torii Pharmaceutical business, in bid to build sales reach and strengthen manufacturing.
The US FDA has ordered compounders of the Danish firm's obesity drug semaglutide to shut up shop later this month, but competition from Eli Lilly is only increasing.
Already dominating in later lines of breast cancer treatment, Enhertu could now displace both chemotherapy combinations and Roche’s Kadcyla in early-stage HER2-positive patients.
