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Boehringer Bids To Go Beyond Slowing IPF

Promising Phase II Data In Lung Disease With High Mortality

 
• By Kevin Grogan

The family-owned German group is the market leader in idiopathic pulmonary fibrosis with Ofev but the big-selling drug has significant side effects and only slows, but does not stop, the progression of the disease. It is hoping that the Phase III-ready compound BI 1015550 will offer a significant improvement.

Boehringer Ingelheim headquarters in Ingelheim, Germany
• Source: Boehringer Ingelheim (dieth+schröder-fotografie)

Boehringer Ingelheim GmbH markets one of the two drugs approved for idiopathic pulmonary fibrosis (IPF) in Ofev but has high hopes that its new treatment could actually stop the lung-scarring disease rather than just slowing it down.

The German group has unveiled positive Phase II data at the American Thoracic Society meeting in San Francisco on BI 1015550, an oral phosphodiesterase 4B (PDE4B) inhibitor

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