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Hanmi/Aptose’s AML Contender Shows Early Promise

Oral Myeloid Kinome Inhibitor Set For Expansion Trials

 
• By Jung Won Shin

Hanmi Pharmaceutical’s hopes for AML drug candidate HM43239, licensed out to Aptose Biosciences, are rising amid accumulating clinical data that appear to put the oral myeloid kinome inhibitor on the right track to registrational studies.

AML
Hanmi’s AML Candidate Nears Registrational Studies • Source: Shutterstock

A series of confirmed complete remissions at various doses in patients receiving Hanmi Pharmaceutical Co., Ltd.’s in-house-developed innovative drug for acute myeloid leukemia (AML), HM43239, are moving the once-daily, oral myeloid kinome inhibitor closer to registrational studies.

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