Roche Holding AG has agreed to pay $250m up front to buy privately held Good Therapeutics, gaining exclusive rights to a preclinical asset and technology centered on the development of PD-1-regulated interleukin-2 (IL-2) receptor agonist therapeutics. IL-2 is a well validated immuno-oncology target but it has remained elusive for drug makers to hit safely and effectively, so Good’s technology aims to work around challenges with this therapeutic target.
Roche and Good Therapeutics, based in Seattle, announced the deal on 7 September. After handing off the PD-1/IL-2 program to...