Domain To Bring First Wholly Owned GCPR Asset Into Clinic

After Building Reputation Through Partnerships

The French firm is going it alone for the first time with a planned Phase I trial for its lead EP4 receptor antagonist in cancer after years of sharing its technology and GCPR expertise with big pharma.    

Birds flying in a group with one lone bird flying separately
Domain Is Forging An Independent Path For The First Time • Source: Shutterstock

Domain Therapeutics S.A. is advancing its first wholly owned drug candidate, DT-9081, into in-human studies later this year, drawing upon its G protein-coupled receptors (GPCR) expertise built up through collaborations.

The firm’s lead program has cleared clinical trial applications at agencies in France and Belgium with a Phase Ia study set to start by year end. DT-9081 is a small-molecule...

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