Zymeworks Deal Expands Jazz’s Potential Oncology Presence

The deal focuses on the HER2-targeting bispecific antibody zanidatamab, in development for multiple solid tumor indications expressing HER2.

Zymeworks and Jazz signed a deal worth up to $1.76bn for the HER2-targeting bispecific antibody zanidatamab • Source: Shutterstock

Zymeworks, Inc. is getting a significant infusion of cash and a commercial partner in a deal with Jazz Pharmaceuticals plc for the HER2-targeted bispecific antibody zanidatamab, while Jazz is gaining a drug that expands the range of targeted solid tumors in its portfolio. But one analyst questioned the size of the deal relative to the therapy’s projected revenue potential.

Jazz and Zymeworks announced the deal on 19 October, whereby Zymeworks will receive $50m up front and a second payment...

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