MEI Gets Another Chance At PI3K Inhibitor With Infinity Merger

Merger plans follow MEI’s recent decision to shelve its own PI3K inhibitor due to class safety concerns. Combined firm will have three clinical oncology candidates, runway into 2025.

M&A
MEI and Infinity announce the latest merger of smaller, clinical-stage biotechs • Source: Shutterstock

Continuing a trend of small companies merging in a tight financial market to increase their runway and R&D shots on goal, MEI Pharma, Inc. and Infinity Pharmaceuticals, Inc. revealed on 23 February that they plan to merge, with a focus on Infinity’s Phase II PI3K inhibitor eganelisib in metastatic head-and-neck cancer as well as two early-stage cancer candidates from MEI.

While both companies are publicly traded, the financing environment is tight across the biopharmaceutical sector, including for clinical-stage companies. (Also see "Finance Watch: Aileron, Talaris, Frequency And The Search For Strategic Alternatives" - Scrip, 21 February, 2023

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