Generation Bio’s LNP DNA-Delivery Platform Gets Big Boost From Moderna

The company aims to deliver DNA via lipid nanoparticles as well as delivering LNPs systemically to tissues beyond the liver and spleen, which the CEO called a “frontier” in an interview.

Moderna signed a deal with Generation Bio for its lipid nanoparticle and DNA-delivery technology • Source: Shutterstock

Generation Bio Co.’s platform technology got a big stamp of approval thanks to a deal with Moderna, Inc. that grants Moderna the option to license Generation Bio’s lipid nanoparticle (LNP) and DNA technology for programs targeted to immune and liver cells. It’s also a demonstration of how Moderna is investing the considerable stash of money it has saved up from sales of its COVID-19 vaccine to rapidly expand its drug development pipeline.

Moderna and Generation Bio announced 23 March that they had made a deal whereby Moderna will be able to advance...

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