AstraZeneca PLC’s danicopan has succeeded in a Phase III trial of paroxysmal nocturnal hemoglobinuria (PNH) patients experiencing extravascular hemolysis (EVH) despite standard of care, a win that could help the company maintain sales of Ultomiris.
AZ’s Danicopan Could Protect Ultomiris After Pivotal Combination Success In PNH
The major’s factor D inhibitor has increased hemoglobin in a subset of paroxysmal nocturnal hemoglobinuria patients when added to a C5 inhibitor, paving the way for an approval that could help protect Ultomiris from competition.
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