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Novartis Aims To Fly High In Kidney Disease With Chinook Buy

Paying $3.2bn Upfront For Two Phase III IgAN Drugs

 
• By Kevin Grogan

Buying Chinook will add a pair of late-stage programs to Novartis's IgAN portfolio which is currently headed by iptacopan but the proposed deal could attract the attention of the FTC.

Chinook
Chinook Lifted By Novartis Interest • Source: Shutterstock

Novartis AG has jumped onto the M&A merry-go-round to pick up Chinook Therapeutics Inc., paying $3.2bn upfront to get hold of two late-stage drugs for the rare kidney disease IgA nephropathy (IgAN).

The Swiss major, which is already developing its oral complement factor B inhibitor iptacopan for IgAN, is acquiring atrasentan, an oral endothelin A receptor antagonist which is currently in the Phase III AGILE study, and zigakibart, a subcutaneous anti-APRIL monoclonal antibody that is scheduled to enter late-stage trials in the third quarter

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