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Paradigm Plots Revival Of Butterfly Skin Drug After Amicus Deal

Regains Rights To Topical Whole-Body Treatment

 
• By Kevin Grogan

Chiesi-owned Amryt and Krystal Biotech have approved treatments for epidermolysis bullosa but Paradigm CEO Robert Ryan tells Scrip that SD-101, a topical cream he helped develop over 20 years ago, has the potential to be offer a far more extensive and efficacious solution for many more sufferers.   

butterfly
• Source: Shutterstock

The main focus for epidermolysis bullosa (EB) treatment may currently be on Krystal Biotech, Inc.'s gene therapy Vyjuvek, but newcomer Paradigm Therapeutics believes a wound-healing agent just acquired from Amicus Therapeutics, Inc. that previously failed late-studies has the potential to help far more patients who have the rare genetic condition where skin can tear at the slightest touch.

Paradigm has completed the acquisition of the worldwide rights of SD-101, a topical whole-body treatment for all subtypes of EB from Amicus

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