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Daiichi Sankyo Comes Out Swinging At WCLC As ADCs Steal Show

 
• By Alaric DeArment

The Japanese drug maker gave multiple presentations on AstraZeneca-partnered Enhertu and other deruxtecan-based ADCs. Plus Gilead presented data on Trodelvy, Amgen showed early frontline data for Lumakras, and J&J’s EGFR-directed bispecific Rybrevant showed a 50% ORR in heavily pretreated patients.

The World Congress on Lung Cancer is taking place in Singapore from 9-12 September • Source: Shutterstock

Antibody-drug conjugates were a feature at the World Congress on Lung Cancer meeting in Singapore, including data from the first ADC that Daiichi Sankyo Co., Ltd. is developing independently of longtime partner AstraZeneca PLC.

The potential competitive positioning of AstraZeneca/Daiichi Sankyo’s TROP2-directed ADC, datopotamab deruxtecan (Dato-DXd), compared with Gilead Sciences, Inc.’s Trodelvy (sacituzumab...

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