BioNTech In Another China ADC Deal, This Time With Medilink

HER3-Targeting Asset

Medilink’s ADC platform, which addresses the antibody endocytosis process, has received its first endorsement from a major international partner in the form of BioNTech.

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BioNTech picks Medilink’s differentiated TMALIN ADC platform in HER3-targeting ADC deal • Source: Shutterstock

Following two separate deals with Duality Biologics, BioNTech SE has inked another antibody-drug conjugate (ADC) collaboration with another Chinese firm, Suzhou Medilink Therapeutics Ltd., in a deal worth up to more than $1bn. At the center of the agreement is YL202, a HER3-targeting candidate, Medilink announced on 12 October.

Key Takeaways
  • In exchange for global rights to YL202, BioNTech will pay Medilink $70m upfront, as well as development, regulatory and commercial milestone payments that could take total deal value to $1bn-plus.

  • HER3-targeting YL202 uses the TMALIN ADC platform, which is effective regardless of antibody endocytosis ability

The collaboration marks Medilink's first major alliance with a leading international partner, which has put in the spotlight the Chinese biotech’s novel ADC platform

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