China

Multiple Chinese HER2 ADCs Close In On Enhertu In Breast Cancer

 

Clinical and regulatory developments in breast cancer for multiple HER-2-targeting antibody-drug conjugates from Chinese firms look set to up the competition for Enhertu.

China Companies’ Out-Licensing Deals ‘Rational’ But Partly Policy-Driven

 
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The acceleration of commercial health insurance was included in national development plans for 2026 released by the Chinese government in the recent “Two Sessions” policy meetings, and appears key for the next generation of innovative drugs to achieve domestic success.

Dizal’s Zegfrovy Snags World-First Phase III Win As Oral Option For Rare-Type NSCLC

 

Dizal's Zegfrovy (sunvozertinib), already approved in the US and China for the second-line treatment of NSCLC with EGFR exon 20 insertion mutations, triumphs in the WU-KONG28 Phase III study in the first-line setting.

Kintor’s Male Hair Loss Drug Returns With Phase III Win

 

Kintor's topical androgen receptor inhibitor KX-826 posts win in China Phase III trial in male androgenetic alopecia, following a Phase III setback in 2023.


Pfizer, Roche Looking Beyond Simple Licensing In China Deals

 
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Multinationals showed up with open arms for partnering with Chinese developers at the recent BIOCHINA meeting, but there were signs approaches are changing and firms are now looking beyond straight licensing.

Almirall Eyes China Dermatology Assets Beyond Simcere Partnership

 

Spanish firm's CSO Karl Ziegelbauer shares with Scrip his views on potential alliances with Chinese and other companies and what Almirall can bring to the table.

Almirall On The Lookout For More China Collaborations

 
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The Spanish company has set up shop in Shanghai to be closer to current and future dermatology partners.

In Brief: Jacobio/AZ’s JAB-23E73 Reports First Clinical Results For Pan-KRAS Inhibitors

 

Clinical Data Readout: Jacobio Pharmaceuticals and AstraZeneca's JAB-23E73, a pan-KRAS inhibitor, stands out among its peers as the first to report preliminary Phase I results after completing the dose escalation phase of a China-based clinical study.


China Grants Global-First Approval To cAMP-biased GLP-1R Agonist For Weight Loss

 
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China has granted a world-first approval to a cAMP-biased GLP-1R agonist, Sciwind's ecnoglutide, for weight management, following convincing Phase III results.

Qilu, Lynk Score Phase III Wins In China Cancer, Atopic Dermatitis Trials

 

Qilu’s bifunctional combo of PD-1 and CTLA-4 antibodies hits its marks in a Phase III cervical cancer trial, while Lynk’s JAK1 inhibitor logs similar win in atopic dermatitis.

UCB In $1bn-Plus Deal For Antengene’s Anti-CD19/CD3 T-Cell Engager

 
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UCB is paying $1bn-plus for global rights to Antengene's ATG-201, an anti-CD19/CD3 T-cell engager, as it looks to build its strength in immunology.

Sanofi Replenishes cGVHD Pipeline With Sino Biopharm’s JAK/ROCK Inhibitor

 

Deal Snapshot: By paying Sino Biopharm up to $1.5bn, Sanofi appears to planning for its new Chinese partner’s JAK/ROCK inhibitor rovadicitinib to pick up where its own Rezurock left off in first-line, chronic graft-versus-host disease.


China Approves Sino Biopharm’s First-In-Class Oral Molecule For 1L Myelofibrosis

 
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China’s National Medical Products Administration grants global-first approval to oral JAK/ROCK inhibitor for adult primary and secondary myelofibrosis.

In Brief: Strong Results Advance DualityBio/BioNTech’s B7H3 ADC Into Phase III CRPC Trial

 

Clinical Data Readout: With a median follow-up of 6.5 months, updated findings from a Phase I/II study of DB-1311 (BNT324) in heavily pretreated mCRPC patients worldwide showed a median radiographic progression-free survival of 11.3 months and a median overall survival of 22.5 months.

Beijing Health Guard’s Trial Pauses Add To China HPV Vaccine Makers’ Distress

 

Amid a wider domestic market downturn, Beijing Health Guard’s three Phase III trials for two of its HPV vaccine candidates were suspended in January and February due to overdue payments to sites.

Biokin’s Iza-Bren Scores Second Phase III OS Win In China Trial

 

Sichuan Biokin Pharmaceutical’s iza-bren hit the co-primary endpoints of OS and PFS in a Phase III clinical study in Chinese patients with triple-negative breast cancer in the second and later-line settings.


Chinese ADC, Cell/Gene Therapy Biotechs Ride Funding Spree

 

2026 has already seen several major new funding rounds for Chinese biopharma ventures, including a $70m financing for CAR-T specialist Oricell and a $40m Angel round for ADC specialist Tosun.

Ascletis Progresses Amylin Obesity Pipeline With View To Collaborations

 
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Chinese company expands its amylin-targeting portfolio in obesity with fast-paced plans for progressing clinical trials in the US and finding partners.

Kangtai Drops Plan for China Vaccine JV With AstraZeneca

 

Kangtai has decided to terminate the original plan for a roughly $400m partnership with AstraZeneca announced in March 2025 which was expected to establish the UK major's first vaccine manufacturing site in China.

A Look At The Next Gen Obesity Pipeline Coming Out Of China

 
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Scrip takes a look at the next generation of innovation in obesity medicines coming out of China and key assets originated in the country set to enter Phase III this year.