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ESMO 2023: Tarlatamab Primed To Take Big BiTE Out Of SCLC Market

 
• By Kevin Grogan

Amgen's DLL3-targeting bispecific T-cell engager could be filed on Phase II data having demonstrated exceptional duration of response in small cell lung cancer patients.

Amgen

The chances of a swift approval for tarlatamab, one of the jewels in Amgen, Inc.'s oncology crown, for small-cell lung cancer have received a major boost following promising and potentially registrational data presented at the European Society for Medical Oncology (ESMO) congress in Madrid.

The US giant presented positive top-line data in August from a Phase II study evaluating tarlatamab, a first-in-class delta-like ligand...

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