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ESMO 23: Concerns Despite Unprecedented Early-Stage Lung Cancer Win For Roche’s Alecensa

 
• By Kevin Grogan

The Swiss group's ALK inhibitor Alecensa improved disease-free survival by 76% in early-stage patients with the mutation, a first for the class, but an ESMO discussant raises questions about toxicity and treatment burden.

ESMO 2023 exterior
• Source: ESMO

Comfortably the market leader in treating advanced anaplastic lymphoma kinase (ALK)-positive lung cancer, the extent of the Phase III success of Roche Holding AG's Alecensa in tackling the early stage of the disease has caused a stir at the European Society for Medical Oncology congress in Madrid.

The Swiss major signalled in September that in the 257-patient Phase III ALINA study, Alecensa (alectinib) achieved an "unprecedented" improvement...

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Glenmark Chief On IGI’s Landmark Trispecific Deal: Strong Data Excited AbbVie

 
• By Anju Ghangurde

Glenmark’s managing director talks about IGI’s billion dollar-plus deal with AbbVie, ISB-2001’s striking data, the BEAT platform, other "exciting" pipeline assets and the "blood, sweat and tears" to get to this stage.

Four Chinese Firms Snag Global First-In-Class Approvals In China

 
• By Dexter Jie Yan

Four Chinese companies have won approvals in China, the first anywhere, for novel drugs for diffuse large B-cell lymphoma, certain types of non-small cell lung cancer and influenza A.

AbbVie Licenses IGI’s ISB 2001 In Second Myeloma Trispecific Deal For 2025

 
• By Alaric DeArment

IGI CEO Cyril Konto said in an interview that his company picked AbbVie for its agility, drug development acumen and expertise in areas like intellectual property and legal affairs.

Investors Back Nuclidium’s Next-Gen Copper-Based Radiopharmaceuticals

 
• By Andrew McConaghie

The Swiss company believes its platform can make radiopharmaceuticals easier to produce and more accessible to patients.

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AbbVie Licenses IGI’s ISB 2001 In Second Myeloma Trispecific Deal For 2025

 
• By Alaric DeArment

IGI CEO Cyril Konto said in an interview that his company picked AbbVie for its agility, drug development acumen and expertise in areas like intellectual property and legal affairs.

Ultragenyx and Mereo Still Confident Despite Setrusumab Slip Up

 
• By Kevin Grogan

The osteogenesis imperfecta drug stumbled in a second interim analysis.

Investors Back Nuclidium’s Next-Gen Copper-Based Radiopharmaceuticals

 
• By Andrew McConaghie

The Swiss company believes its platform can make radiopharmaceuticals easier to produce and more accessible to patients.