Amgen, Inc. caused a stir at the European Society for Medical Oncology meeting in Madrid with promising data for its small-cell lung cancer offering tarlatamab but the reception for a late-stage study looking at a combination of its KRAS G12C inhibitor Lumakras and Vectibix for colorectal cancer was a bit cooler.
ESMO 23: Amgen's Lumakras/Vectibix Combo Clinches Colorectal Cancer Win
The higher dose of Amgen's Lumakras combined with Vectibix has demonstrated significant superiority in progression-free survival over investigator's choice of therapy in KRAS G12C-mutated metastatic colorectal cancer but the discussant at the combo's ESMO presentation wants to see overall survival data before getting too excited.

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