Crunch Time For Cytokinetics As Aficamtem Readout Approaches

03 Nov 2023

The takeover target will present eagerly anticipated Phase III data on the cardiac myosin inhibitor for obstructive hypertrophic cardiomyopathy before the end of the year and potential suitors are preparing to pounce, according to the rumor mill.

Human Heart network — • Source: Shutterstock

Cytokinetics, Inc. is in confident mood as it edges closer to a critical late-stage readout for its cardiovascular hopeful aficamten and the US biotech is once again being mentioned as a potential takeover target.

Robert Blum, CEO of the South San Francisco, CA-headquartered firm, used the third quarter call to stress that aficamten "remains...

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

Start your 7-day free trial
Explore trusted news, analysis, and insights
Access comprehensive global coverage
Enjoy instant access – no credit card required

Start Free Trial

Already a subscriber?

Lilly Agrees To Acquire PCSK9 Base-Editing Partner Verve

17 Jun 2025

• By Joseph Haas

Instead of opting in on Phase II-ready PCSK9-targeted VERVE-102, Lilly will buy its partner for up to $1.3bn. Analysts call the deal a bargain for Lilly, but fair to Verve.

Merck & Co.’s Enlicitide Poised To Be First Oral PCSK9 Inhibitor To Market

09 Jun 2025

• By Jessica Merrill

The company announced positive data from two Phase III trials testing the cholesterol-lowering medicine.

In Brief: Tourmaline Reports Positive Topline Phase II Results for Pacibekitug In CKD

21 May 2025

• By Sushmita Panda

Based on first positive results for any quarterly IL-6 inhibitor, company plans to initiate Phase III cardiovascular outcomes trial.

In Brief: Essence Raises Ionis Tryngolza Hypertriglyceridemia Filing Hopes

20 May 2025

• By Sushmita Panda

Tryngolza has met endpoints in a moderate hypertriglyceridemia trial. Positive results in severe disease in Q3 could allow for a filing for a broader patient population than its currently approved indication of familial chylomicronemia syndrome.