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Sanofi Ramps Up In Rare Diseases With Inhibrx Buy

 
• By Kevin Grogan

The French major is paying up to $2.2bn to get access to Inhibrx’s alpha-1 antitrypsin deficiency candidate and to take a stake in the rest of the California-based biotech’s portfolio.

Sanofi
• Source: Sanofi

Sanofi has hit the acquisition trail again to strengthen its rare disease pipeline, buying US biotech Inhibrx, Inc. and what it hopes will be a best-in-class asset to treat alpha-1 antitrypsin deficiency (AATD).

At the heart of the deal is INBRX-101, a recombinant human AAT-Fc fusion protein that works by inhibiting neutrophil elastase, an enzyme responsible for lung tissue damage in patients with AATD, an inherited rare disease that is also associated with liver fibrosis

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