From Ranbaxy Crisis To Enhertu Success: How A New CEO Reshaped Daiichi Sankyo

When George Nakayama was assigned to lead Daiichi Sankyo despite his atypical background, the firm was facing several crises, including a probe into the acquisition of Ranbaxy and a looming patent cliff. So, what made him decide to focus on ADCs while reshaping the entire company? 

Communication was always the key for Daiichi Sankyo's transformation under Nakayama's leadership.
Communication was always the key for Daiichi Sankyo's transformation under Nakayama's leadership. • Source: Shutterstock

It was just several years ago when Daiichi Sankyo Co., Ltd.’s first antibody-drug conjugate (ADC) Enhertu (trastuzumab deruxtecan) was launched in the US, helped by the Japanese company’s largest collaborative deal ever at the time, with AstraZeneca PLC.

The ADC has been the firm’s mainstay since then, becoming a blockbuster on the back of its

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