Gossamer Partners With Chiesi To Accelerate Seralutinib Development

Cash Will Fund Trial In Second, Larger Indication

Already in Phase III for PAH, Gossamer said it can take seralutinib into Phase III for PH-ILD at least four years earlier than planned under its alliance with respiratory disease expert Chiesi.

Pulmonary hypertension is a cardiovascular condition characterized by high blood pressure in the pulmonary arteries 3D rendering
Topline Phase III data in PAH are expected in Q4 2025 • Source: Shutterstock

Gossamer Bio, Inc. is testing its inhaled kinase inhibitor seralutinib in a Phase III clinical trial as a potential disease-modifying treatment for pulmonary arterial hypertension (PAH), but has its eyes on the larger, less crowded market of pulmonary hypertension associated with interstitial lung disease (PH-ILD). Now, after signing a deal with Chiesi Farmaceutici S.p.A., Gossamer has the resources to begin a Phase III trial in PH-ILD at least four years sooner than planned.

Key Takeaways
  • Gossamer, down to its last drug candidate, sees a path to blockbuster status with seralutinib and can expand from PAH into a second indication of PH-ILD faster with new partner Chiesi.

San Diego-based Gossamer and the Italian respiratory and rare disease specialist Chiesi announced their global collaboration and license agreement on...

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