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Maze Finds A Way As Shionogi Signs On To Develop Pompe Drug

 
• By Alaric DeArment

Months after an antitrust lawsuit challenged its deal with Sanofi and raised uncertainty about the future of MZE001, Maze secured a new partner for potentially the first oral Pompe disease drug.

• Source: Shutterstock

A year after attempting to partner with French drug maker Sanofi – only to have US regulators stop the deal over antitrust concerns – Maze Therapeutics has entered into a similar partnership with Shionogi & Co. Ltd.for the oral Pompe disease drug MZE001.

The companies announced the exclusive worldwide collaboration on 10 May, whereby Shionogi will pay Maze $150m up front, plus undisclosed milestone payments based on development, regulatory and commercial achievements, along with tiered royalties on future net sales

Key Takeaways

  • Shionogi reached out to Maze and made a deal for an exclusive global license for MZE001 in Pompe disease.

  • The deal includes a $150m upfront payment plus undisclosed milestone fees for what could be the first oral treatment for the lysosomal storage disorder

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