BMS Returns TIGIT Bispecific To Agenus Amid Pipeline Reshuffle

Agenus said in an SEC filing that Bristol Myers Squibb was sending back AGEN1777, which entered into Phase II development earlier this year.

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Agenus Inc. said Bristol Myers Squibb Company returned rights to the TIGITxCD96-targeting bispecific antibody AGEN1777, the second piece of unwelcome news in less than a month for its immuno-oncology programs.

In a Securities and Exchange Commission filing on 2 August, Agenus said BMS had informed it that it would return AGEN1777 and terminate the three-year-old license agreement between the two companies for the product

Key Takeaways
  • In an SEC filing, Agenus said BMS had returned AGEN1777, which it had licensed in 2021 in a deal then worth potentially more than $1.5bn.

  • Agenus said the decision by BMS was part of a strategic realignment of its development pipeline

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