New Domestic Partnerships Help DualityBio Become China ADC Bellwether

China's Duality Biologics, founded in 2020, has developed two-thirds of its clinical-stage antibody-drug conjugates by combining antibodies acquired from domestic peers with its proprietary linker-payload platform.

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Chinese ADC players increasingly combining strengths in linker-payload platforms and antibodies • Source: Shutterstock

Duality Biologics (DualityBio), one of the Chinese firms making waves on the world antibody-drug conjugate stage since 2022, has revealed four new domestic antibody partnerships that put the fledgling biotech on a course to becoming an ADC bellwether in the country.

Key Takeaways
  • China's DualityBio reveals details of new domestic antibody partnerships that are helping it accelerate the development of four clinical-stage ADCs.

  • Those with WuXi Biologics and Harbour BioMed are focused on B7-H3-targeting DB-1311 and B7-H4-targeting DB-1312, respectively

The disclosures came as DualityBio on 26 August filed for an initial public offering on the Hong Kong Stock Exchange, on the back of a fully diluted valuation of $270m

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