How Charl Van Zyl Is Reimagining Lundbeck

Lundbeck CEO Charl van Zyl spoke with In Vivo about the Danish company’s multipronged transformation, one that involves a rethink of company culture, pipeline strategy and a sharpened focus on innovation in rare neurological disorders.

Charl van Zyl
Charl van Zyl, CEO, Lundbeck (Søren Svendsen/Lundbeck)
Key Takeaways
  • Lundbeck's foundation ownership enables CEO van Zyl to prioritize long-term R&D investment in precision neurology despite looming patent cliffs.
  • The $2.6bn Longboard acquisition secures bexicaserin (patent protection until 2041) as a critical growth bridge beyond Rexulti's 2029 patent expiry.
  • Van Zyl has transformed Lundbeck's pipeline from predominantly early-stage assets to four Phase III programs by 2026, balancing current performance with future growth potential.

Amid an industry-wide scramble to secure growth beyond looming patent cliffs, Denmark’s Lundbeck is undergoing a strategic transformation under CEO Charl van Zyl

“We are a company that’s revitalizing and reinventing ourselves,” van Zyl told In Vivo

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