New Science

Ginkgo Bioworks' LLM Addresses mRNA Stability

 
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Gingko Bioworks has released a large language model designed to improve mRNA stability.

CCRM: Building A Global Regenerative Medicine Ecosystem From Canadian Roots

 
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The Centre for Commercialization of Regenerative Medicine has spent over a decade crafting a cell and gene therapy ecosystem in Canada. Now it is replicating the model abroad.

From Stem Cells To Organoids: Roche’s Hans Clevers’s Quest To Transform Drug Development

 
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This is Part 1 of a 2-part profile of Hans Clevers, Head of Pharma Research and Early Development at Roche.

Artiva Leverages Unmodified NK Cells To Challenge CAR-T Paradigm

 
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Artiva Biotherapeutics is hoping its NK cell therapy approach, which uses un-engineered cells, will prove effective in both oncologic and autoimmune indications and safe enough to be given in the community setting.


Podcast: How Fauna Bio Gleans Therapeutic Insights From Animals

 
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In Vivo speaks with Ashley Zehnder, CEO of Fauna Bio, a company using AI to identify drug targets based on natural disease resistance in animals.

Podcast: The Future Of Immunotherapy

 
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In this episode of the In Vivo podcast, Harvard immunologist and co-founder of early-stage biotech Corner Therapeutics, Jonathan Kagan, talks about harnessing the power of the innate immune system by weaponizing dendritic cells and creating immunotherapies that are safer and more durable.

TechBio Investment Snapshot: Funding, Alliances And Collaboration

 
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Data provided by Biomedtracker show that data-driven methodologies within R&D are propelling life sciences to unprecedented advancements. It is making drug development faster, more efficient and more personalized.

Into 2025: APAC’s Medtech Innovation And Investment Climate Emerging Into The Light

 
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Medtech innovators in the APAC region have in recent years seen a slowdown in investment following a combination of rising costs, supply chain challenges and inflationary pressures. But there is light at the end of the tunnel, says MedTech Innovator APAC leader Fredrik Nyberg.


Biopharma Plumps Pipeline With Healthy Weight Loss Candidates

 
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Despite the stellar success of the class so far, biotech is now looking past GLP-1s to more tolerable, sustainable approaches to obesity.

Podcast: Treating Rare Diseases With tRNA

 
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In this episode of the In Vivo podcast Michelle Werner, CEO of Alltrna, discusses using tRNA as a therapeutic modality for rare diseases.

Podcast: Mapping The Immune System To Predict Immune Responses

 
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Israeli-American biotech Immunai is mapping the immune system and using AI to predict immune responses to drugs.

The Future Of Inflammation: The Inflammasome And Beyond

 
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Novel targets for managing inflammation hold the promise of greater efficacy and safety for diseases not widely viewed as inflammatory in nature.


Freely Available Microbiome Data ‘Atlas’ Could Provide Industry Boost

 

King’s College London has released a freely available ‘Human Gut Microbiome Atlas’ to help researchers better understand how microorganisms in the gut impact disease. 

Formation Secures Huge Series D For AI Platform Growth

 

Biopharmaceutical venture capital fundraising is on the rise in 2024. In late June, Formation Bio secured a mega financing, raising $372m via a series D round led by a16z and Sanofi. 

‘Potentially Groundbreaking’ – Grey Wolf Advances IO Technology

 

Grey Wolf Therapeutics has secured $99m via an expanded series B financing to advance its antigen modulation approach in cancer and to further explore its use in autoimmune disease indications.

The Biotech Balancing Act: Long-Term Vision Vs. Inflection Points

 
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Tuyen Ong, a CEO-partner at Flagship Pioneering and CEO of Ring Therapeutics, discusses the importance of balancing short-term wins with a longer-term vision when building a biotech.   


Regeneron Aiming To Be A Cell And Gene Medicine ‘Powerhouse’

 

Increased R&D spending, program acquisitions and a soaring headcount – Regeneron has seen significant growth over the past 5 years. The company is focused on marrying its antibody technologies with its expanding cell and gene therapy pipeline. 

China’s CAR T-Cell Therapy Industry Booms With Shanghai At Center

 
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According to China Pharmaceutical Innovation and Research Development Association, in the first quarter of 2024 a total of 44 cell therapies in the domestic cell therapy field made clinical application progress, including 28 immune cell therapies and 16 stem cell therapies.  

ASCO 2024 In Review: A Webinar With Citeline Analysts

 

Citeline analysts offered deep dives into some of the data presented at the American Society of Clinical Oncology annual meeting, including both major highlights and some lesser-known finds.   

‘A New Era’: What Next For CRISPR Gene Editing After First Approval?

 
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Emerging out of a landmark 2023, CRISPR companies and researchers are pushing in vivo therapies and other approaches closer to the clinic and potential approval.