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Novartis Joins MRGPRX2 Race Through $800m+ Kyorin Deal

Addition To CSU Portfolio

 
• By Lisa Takagi

Swiss major gains global rights to preclinical asset as it joins race for MRGPRX2 antagonists in urticaria, where some same-class rivals are already in Phase II.

Kyorin Novartis deal
$800m deal with Kyorin has brought another CSU candidate to Novartis. (Shutterstock)

Novartis Pharma has expanded its immunology pipeline through a global, $832.5m licensing deal for a small molecule antagonist of Mas-related G protein-coupled receptor X2 (MRGPRX2) developed by Japan-based Kyorin Pharmaceutical.

KRP-M223 adds to the Swiss firm’s urticaria portfolio, which already includes the oral BTK inhibitor

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