Paratek To Acquire Optinose, Expanding Portfolio Beyond Antibiotics

Paratek agrees to acquire Optinose in a “take-private” deal valued at $330m, adding chronic rhinosinusitis product Xhance to its antibiotic Nuzyra.

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Paratek will acquire Optinose and CRS drug Xhance

Less than two years after being taken private by Gurnet Capital and Novo Holdings, Paratek Pharmaceuticals has agreed to a merger with Optinose that will expand its product portfolio beyond the antibiotic Nuzyra (omadacycline). The transaction unveiled on 20 March is valued at approximately $330m, although more than a third of the potential value is tied to commercial performance of Optinose’s Xhance.

Key Takeaways
  • Paratek will expand its portfolio to include chronic rhinosinusitis drug Xhance in a take-private merger with Optinose.
  • Xhance, indicated to treat CRS patients with or without nasal polyps, has a much larger patient base after a 2024 label expansion

Like its June 2023 acquisition, which included a contingent value right (CVR) connected to sales of Nuzyra, Paratek’s planned acquisition of Optinose includes a CVR and will delist the Yardley, PA-based specialty firm from the Nasdaq exchange

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