Emerging Company Profiles

Seraxis Takes Its Islet Cell Tech Into The Clinic

Seraxis Takes Its Islet Cell Tech Into The Clinic

 

Emerging Company Profile: The Maryland-based biotech is working on a functional cure for type 1 diabetes that is similar to Vertex’s VX-880 – but with some key differences.

Early Data In Hand, Vesper Bio Takes On GSK And Alector

Early Data In Hand, Vesper Bio Takes On GSK And Alector

 

Emerging Company Profile: Danish group Vesper Bio is advancing an oral sortilin inhibitor in frontotemporal dementia, and is aiming to get to market in a similar timeframe to its much larger rivals.    

Empress Looks To The Body’s Internal Chemistry For Drug Leads

Empress Looks To The Body’s Internal Chemistry For Drug Leads

 
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Emerging Company Profile: Backed by Flagship Pioneering, Empress deploys its Chemilogics platform to seek leads for small molecule therapies in inflammation, immunology, cancer and metabolic disease.

Mythic Therapeutics Faces An Acid Test

Mythic Therapeutics Faces An Acid Test

 

Emerging Company Profile: Efficacy data on the young group’s first pH-engineered antibody-drug conjugate could come next year, and potential partners will be watching.    


Emergex Goes To Battle Against ‘The Nasties’

Emergex Goes To Battle Against ‘The Nasties’

 

Emerging Company Profile: The eight-year-old vaccine firm is planning clinical trials in the Philippines and Brazil to see how its synthetic viral peptide vaccine technology stands up against coronaviruses and dengue fever.

PureTech Hopes For A Second Lightning Strike

PureTech Hopes For A Second Lightning Strike

 

Emerging Company Profile: Seaport Therapeutics believes its technology can alter old drugs to remove their flaws. Just how closely can it follow the example set by Karuna?    

Kiromic Looks To Prove Itself In Lung Cancer

Kiromic Looks To Prove Itself In Lung Cancer

 

Emerging Company Profile: Encouraging, but early, data on a gamma-delta T-cell therapy could position Kiromic BioPharma for deal-making.    

Ambitious AAX Wants To Be Key Player In Next-Generation Antibodies

Ambitious AAX Wants To Be Key Player In Next-Generation Antibodies

 
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Emerging Company Profile: The Swedish biotech’s CEO Maria Lisa Knudsen believes that the firm’s two technologies make it an attractive prospective partner for big pharma. 


Emerging Company Profile: Chinese siRNA Specialist Sirius All In On Cardiovascular Disease

Emerging Company Profile: Chinese siRNA Specialist Sirius All In On Cardiovascular Disease

 

Sirius has joined the race to develop China’s first homegrown RNAi therapy and is backing its assets’ potential in chronic cardiovascular disorders, including possible once-yearly dosing, the venture’s CEO tells Scrip in an interview.

Freya Biosciences Has $38m And A Plan To Change Women’s Lives

Freya Biosciences Has $38m And A Plan To Change Women’s Lives

 

Emerging Company Profile: Armed with a new tranche of funding, the Danish group is aiming to improve the lot of infertile couples by altering the microbiome of patients with dysbiosis.  

Kura Continues Araxes Legacy With New Menin And FTI Focuses In Cancer

Kura Continues Araxes Legacy With New Menin And FTI Focuses In Cancer

 
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Emerging Company Profile: The US biotech is advancing a pipeline of precision medicines targeting menin and farnesyltransferase for liquid and solid tumors, respectively, building on the work of two pioneering companies in the KRAS space.  


SpyGlass To Boost Ophthalmic Drug Adherence With Intraocular Delivery Platform

SpyGlass To Boost Ophthalmic Drug Adherence With Intraocular Delivery Platform

 
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Emerging Company Profile: The US biotech SpyGlass is gearing up for a Phase I/II trial in glaucoma after recently closing a $90m fundraising to help advance its intraocular delivery platform to address poor treatment adherence in chronic eye diseases.  

Evommune Looks To Advance Broad Pipeline Of Autoimmune Drugs

Evommune Looks To Advance Broad Pipeline Of Autoimmune Drugs

 

Emerging Company Profile: With experienced leadership and new financing, Evommune is developing a topical IRAK4 inhibitor for atopic dermatitis and earlier-stage systemic drugs for various conditions.

Iksuda Aims For Best-In-Class Cancer ADCs With Toolbox Approach To Technology

Iksuda Aims For Best-In-Class Cancer ADCs With Toolbox Approach To Technology

 
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Emerging Company Profile: While the UK biotech boasts a promising in-house platform technology, it believes a less restrictive approach to R&D could help it develop superior antibody-drug conjugates for cancer.  

Kinaset Advances Inhaled Pan-JAK Inhibitor For Broad Use In Severe Asthma

Kinaset Advances Inhaled Pan-JAK Inhibitor For Broad Use In Severe Asthma

 
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Emerging Company Profile: The US biotech acquired its sole asset from CDMO Vectura in 2020 and is now gearing up for a Phase II proof-of-concept trial in severe asthma to help address the unmet need in non-eosinophilic patients.  


NextPoint Could Treat PD-L1 Negative Cancer Patients With HHLA2-Targeted Approach

NextPoint Could Treat PD-L1 Negative Cancer Patients With HHLA2-Targeted Approach

 
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Emerging Company Profile: Backed by strong academic talent and a recent $80m fundraising, the US biotech is on a mission to address the unmet medical need in PD-L1 negative cancer by targeting the HHLA2 pathway.  

EvolveImmune Targets Lymphoma With Novel T-Cell Engagers Harnessing CD2

EvolveImmune Targets Lymphoma With Novel T-Cell Engagers Harnessing CD2

 
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Emerging Company Profile: The firm’s use of the CD2 co-stimulant in its T cell engager design could significantly boost anti-tumor efficacy while addressing T cell exhaustion, with a first-in-human trial planned for 2024.  

Inozyme Targets Underserved Mineralization Disorders Market With First-In-Class Enzyme Therapy

Inozyme Targets Underserved Mineralization Disorders Market With First-In-Class Enzyme Therapy

 
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Emerging Company Profile: Fresh from a $73m follow-on offering last year, the US biotech is readying its lead asset for a pivotal trial in ultra-rare but debilitating mineralization disorders that affect infants and children.  

ThirtyFiveBio Makes Its Debut With First-In-Class GPR35 Antagonist Approach

ThirtyFiveBio Makes Its Debut With First-In-Class GPR35 Antagonist Approach

 
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Emerging Company Profile: Backed by $20m in seed funding, the UK firm is going against the grain by antagonizing, instead of agonizing, G protein-coupled receptor 35 with an eye to treating colorectal cancer and other gastrointestinal conditions.