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CSPC’s Global-First Monospecific ADC Promising In Advanced NSCLC

But Biokin Hot On Heels With Bispecific

 
• By Xu Hu

CSPC’s SYS6010, the first monospecific EGFR-targeting antibody-drug conjugate in the clinic for advanced NSCLC, has shown Phase I promise, but could face close competition with another China-originated bispecific.

Two assets are ready to compete
CSPC's EGFR-targeting ADC SYS6010 showed favorable efficacy in Phase I, especially in patients with EGFR-mutant NSCLC who were resistant to previous EGFR-TKI treatments. (Shutterstock)

Chinese firm CSPC Pharmaceutical has presented promising Phase I results for its first-in-class antibody-drug conjugate (ADC) SYS6010 in non-small cell lung cancer (NSCLC), but the contender is facing close competition from another domestic company.

The therapy conjugates an EGFR antibody with the topoisomerase I inhibitor JS-1 and is the first monospecific EGFR-targeting ADC to...

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Xu Hu

Read more by Xu Hu

Xu is a senior reporter and covers aspects on policy and regulations in China pharma industry within the APAC Pharma news team.

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