Cullinan/Taiho’s Zipalertinib Stands To Benefit From A Clear Market

The two companies announced positive topline results for the drug in pretreated EGFR exon 20 insertion mutation NSCLC, a market that Takeda vacated in 2023.

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Cullinan Therapeutics and Taiho have a significant market opportunity with zipalertinib after successful results in the Phase I/II REZILIENT1 trial among previously treated non-small cell lung cancer (NSCLC) patients whose disease harbors epidermal growth factor receptor (EGFR) exon 20 insertion mutations.

The companies announced topline results on 28 January of the Phase IIb portion of the trial for zipalertinib, also known as CLN-081 and TAS6417, saying that it met the primary...

Key Takeaways
  • Cullinan and Taiho announced positive topline results from the Phase I/II REZILIENT1 trial of zipalertinib.
  • The companies plan to present data from...

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