Dermatological

Jefferies 25: Leo Ready To Leap Into More Deals

 
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CEO Christophe Bourdon tells Scrip that the phone is ringing as the Danish drugmaker aims to become ‘the go-to partner for anything in dermatology.’

Arcutis Swings Into Profit As Skin Therapy Soars

 
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Sales of Zoryve comfortably exceeded consensus in the third quarter and both the foam and cream formulations are selling well across its dermatological indications.

J&J Could Be Latest Protagonist In M&A Merry-Go-Round

 
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More deals could be on the way as the US giant is rumored to be eyeing the acquisition of its icotrokinra development partner.

Apogee Adds To Cash Pile Ahead Of A Pivotal 2026

 
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The US biotech has raised $300m to advance its atopic dermatitis candidate towards Phase III trials next year.


Galderma Punches Above Its Weight Against Dermatology Goliaths

 
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The Swiss group is more than holding its own against Dupixent for prurigo nodularis and is looking to make further inroads into Sanofi and Regeneron's blockbuster's market share in atopic dermatitis.

Novartis Pipeline-In-A-Product Remibrutinib Secures First Approval

 
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The Swiss major's oral BTK inhibitor gets the green light in the US for chronic spontaneous urticaria.

MoonLake Loses Its Luster With Mixed Sonelokimab Data

 
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The Swiss company remains bullish about the drug’s prospects for hidradenitis suppurativa but its stock has collapsed by 90% after hit-and-miss Phase III trial results.

EADV: UCB’s Bimzelx Primed To Maintain Pole Position in HS

 
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The Belgium-based group has collected heaps of long-term efficacy and safety data which will help stave off the competition.


EADV: Affibody’s Izokibep Back On The HS Radar

 
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Its Phase III data compare favorably with same-class Cosentyx and Bimzelx in hidradenitis suppurativa, and the company is now seeking a partner.

EADV: Ascletis/Sagimet’s Acne Drug Shows Rapid Efficacy In China Phase III Trial

 

Ascletis presented updated results at EADV showing denifanstat could significantly improve acne conditions versus placebo in Chinese patients after four weeks of treatment.

EADV: Leo Makes A Big Leap With Eczema Drug Temtokibart Set For Phase III

 
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CSO Jacob Thyssen tells Scrip that the monoclonal antibody which blocks the IL-22RA1 receptor subunit is a very safe and effective option to treat the chronic inflammatory skin disease.

EADV: Incyte’s Povorcitinib Wins Stack Up, Will It Be Enough To Hedge Jakafi Loss?

 
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With patent expiry for its blockbuster blood cancer drug Jakafi on the horizon, Incyte will need to translate these povorcitinib wins from clinic to market.


EADV: Sanofi Smiles Again As Brivekimig Blooms In HS Study

 
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The dual TNFα/OX40L drug comfortably beat placebo in reducing symptoms of hidradenitis suppurativa but no news on Phase III plans yet.

Eyes On Icotrokinra As J&J Submits Oral Psoriasis Therapy

 
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The EMA is reviewing the IL-23-targeting oral peptide which the company claims will transform the plaque psoriasis treatment paradigm.

Junshi Eyes China Filing for IL-17 Antibody In Psoriasis After Phase III Win

 

The drug will face competition from established IL-17 therapies such as Cosentyx, Bimzelx and Taltz, while overall market growth is expected to be supported by newer interleukin inhibitors and rising prevalence.

Sanofi Shares Slide Despite Amlitelimab Eczema Win

 
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The OX40 ligand-targeting drug’s efficacy is seen as light compared with existing therapies.


Leo Keeps On Profitable Path With Solid H1 Sales Growth

 
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The Danish firm's atopic dermatitis drug Adbry is performing well despite strong competition from Sanofi/Regeneron’s Dupixent.

UCB Takes A Bow as Bimzelx HS Launch Achieves Lift-Off

 
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The Belgian company has raised its outlook for full-year sales following a strong launch for Bimzelx in hidradenitis suppurativa in the first half of 2025.

Vyne Seeks Partner For Repibresib After Phase IIb Vitiligo Fail

 

The Phase IIb study failed its primary and a key secondary endpoint, but showed activity on another key secondary and an exploratory endpoint.

Leo Looks To Grow In US After Hand Eczema Cream Approval

 
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The Danish medical dermatology specialist boosts its sales force ahead of the launch of Anzupgo.