Immunological

Gilead Hands Galapagos A Rebuild Opportunity With Ouro Buyout

 
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The deal, which could be worth over $2bn, looks to bolster Gilead's growing immunology franchise while also granting long-time partner Galapagos a chance at a future royalty stream.

Sanofi, Kali Sign Deal For Trispecific Antibody In Autoimmune Disease

 

Deal Snapshot: The French drugmaker gains rights to the anti-CD19xBCMAxCD3 candidate, which is designed to have the benign safety profile considered especially important in immunology.

Apogee’s Atopic Dermatitis Drug Shows Promise, But Can It Challenge Dupixent, Ebglyss?

 

With Phase III plans underway and Part B data from its APEX trial due in 2026, Apogee is banking on zumilokibart's extended dosing advantage compared with rivals.

Aclaris Advances Atopic Dermatitis Ambitions

 
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Phase II results evaluating the anti-TSLP drug bosakitug are expected in the fourth quarter. Aclaris is pitching the asset as having best-in-class potential in a currently open field.


With FDA Approval, Icotyde Wades Into Competitive Psoriasis Market

 

The drug is the first oral IL-23 receptor antagonist to clear the US FDA. Johnson & Johnson and partner Protagonist Therapeutics are banking on its convenience as well as efficacy and safety to make the drug competitive.

UK Biotech Quell Launches Trial To ‘Chill, Not Kill’ With Tregs

 

The biotech believes its Treg, QEL-005, can surpass existing therapies by modulating a range of pro-inflammatory mechanisms in complex immune conditions.

UCB’s BOLD Plans For Pipeline-In-A-Product Bimzelx Are Paying Off

 
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As the Belgian firm's blockbuster beats AbbVie's Skyrizi in a head-to-head psoriatic arthritis study.

Vertex Ratchets Up Competition In IgAN With Povetacicept Phase III Win

 
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Povetacicept’s Phase III results strengthen Vertex’s push to expand beyond cystic fibrosis, with the company expected to complete the drug’s rolling submission by the end of March.


Pfizer Tries Again In Atopic Dermatitis, This Time With A Trispecific

 

The company is advancing tilrekimig into Phase III development based on positive Phase II efficacy data that suggest a potential improvement over biologic standard of care Dupixent.

Qilu, Lynk Score Phase III Wins In China Cancer, Atopic Dermatitis Trials

 

Qilu’s bifunctional combo of PD-1 and CTLA-4 antibodies hits its marks in a Phase III cervical cancer trial, while Lynk’s JAK1 inhibitor logs similar win in atopic dermatitis.

As Hudson Departs, How Can Sanofi Return To R&D Success?

 

Sanofi gets its new CEO next month, and Belén Garijo will be confronted with hard choices on how to improve the firm's hit and miss R&D record.

Hansa Takes Step Towards US Market For Kidney Transplant Drug

 

Hansa Biopharma was not awarded a priority review for imlifidase but analysts nevertheless predict an ‘inflection point’ for the Swedish company.


Immunology, Obesity And Other Insights From The TD Cowen Healthcare Conference

 

AbbVie chief scientific officer Thakkar talked about ways to avoid pitfalls in immunology studies, while Neurocrine chief scientific officer Onyia outlined the company’s new obesity strategy, among other updates.

UCB In $1bn-Plus Deal For Antengene’s Anti-CD19/CD3 T-Cell Engager

 
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UCB is paying $1bn-plus for global rights to Antengene's ATG-201, an anti-CD19/CD3 T-cell engager, as it looks to build its strength in immunology.

Sanofi Replenishes cGVHD Pipeline With Sino Biopharm’s JAK/ROCK Inhibitor

 

Deal Snapshot: By paying Sino Biopharm up to $1.5bn, Sanofi appears to planning for its new Chinese partner’s JAK/ROCK inhibitor rovadicitinib to pick up where its own Rezurock left off in first-line, chronic graft-versus-host disease.

Priovant’s Brepocitinib May Launch Sooner Than Expected

 

The US FDA gave priority review to the JAK1/TYK2 inhibitor, moving the Roivant company’s potential launch date from early 2027 to September 2026.


Novartis Forges Ahead With Rhapsido For Food Allergy

 
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The Swiss major's immunology chief Angelika Jahreis tells Scrip of her high hopes for the potential pipeline-in-a-product.

Asahi Kasei Grows Pharma Business Via M&A With Niche-Focused Strategy

 
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The Japanese industrial material group expands its global presence with a strategic niche focus on immunology, organ transplantation, and severe infectious diseases.

Generate’s $400m IPO Adds To Biotech Bounceback

 

The Flagship Pioneering company has completed the biggest initial public offering of 2026 so far, providing encouragement for more cash-hungry biotechs seeking a public listing.

Boehringer Licenses Preclinical Immunology Program From UK’s Sitryx In $500m-Plus Deal

 

Boehringer Ingelheim has strengthened its immunology research pipeline by licensing Sitryx’s preclinical oral small molecule program targeting immune-driven diseases.