Boehringer Plans Filing For Nerandomilast After Second Phase III Hits

The PDE4B inhibitor showed improvement in lung function in patients with progressive pulmonary fibrosis in a second positive Phase III trial in pulmonary fibrosis.

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Boehringer Ingelheim’s phosphodiesterase 4B (PDE4B) inhibitor nerandomilast has demonstrated efficacy in a second Phase III trial, this time in patients with progressive pulmonary fibrosis (PPF). The company announced on 10 February that it will file nerandomilast with the US Food and Drug Administration and other global regulators for both PPF and idiopathic pulmonary fibrosis (IPF).

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