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CellGate Inc.

Scientists at CellGate Inc. say they have demonstrated that linking short peptide polymers of the amino acid arginine to a drug molecule will both increase the molecule's water solubility and help get it through the cell membrane. Moreover, this proprietary strategy for enhancing drug bioavailability appears to work with any class of compound. Harnessing this universal transporter technology, CellGate plans to build a service business around taking well-characterized molecules and turning them into better drugs.

Scientists at CellGate Inc. say they have demonstrated that linking short peptide polymers of the amino acid arginine to a drug molecule will both increase the molecule's water solubility and help get it through the cell membrane. Moreover, this proprietary strategy for enhancing drug bioavailability appears to work with any class of compound. Harnessing this universal transporter technology, CellGate plans to build a service business around taking well-characterized molecules and turning them into better drugs.

Company scientific founder Jonathan Rothbard left ImmuLogic Pharmaceutical Corp. in late 1994 for Stanford University School of Medicine to study the mechanisms by which molecules penetrate the plasma...

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