A preview of the emerging health care companies profiled in the current issue of Start-Up. This month's profile group, Protein Manufacturing Start-Ups, features profiles of Chesapeake PERL Inc., Chlorogen Inc., ProteomTech Inc. and Psyche Pharmaceuticals Inc. Plus these Start-Ups Across Health Care: ArgoLink Inc., Confirma Inc., FivePrime Therapeutics Inc. and QuantomiX Ltd.
Start-Ups across Health Care
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The cell and gene therapy (CGT) clinical trial landscape in general and CAR-T cell clinical trials in particular are a special focus for the FDA, EMA, and other regulatory agencies. The whole industry is thus aware of the recent FDA safety investigation and requirements for labeling CAR therapy products.
Entrepreneurialism is in the blood of Israel’s medtech innovators, but in a changing medtech world, the local ecosystem must address funding gaps and manufacturing and infrastructure needs. So says Ruti Alon, experienced Israeli medtech leader, investor and co-chair of the Biomed Israel conference.
During Q2, biopharma merger and acquisition deal value reached $24.6bn and drew in $60.7bn in potential deal value from alliances. Device company M&A values reached $223m, while in vitro diagnostics and research tools players’ M&A activity totaled $802m.
Facing rising costs and tighter regulations, PBMs and insurers are accelerating the shift to value-based drug coverage, demanding stronger proof of therapeutic and economic benefit from pharma.