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GSK's Virtual-Proof-of-Concept Unit in Tune with Lilly's Chorus

Many readers will have heard of Eli Lilly's Chorus initiative, designed to drive compounds through to proof-of-concept as cheaply and quickly as possible. A less well-publicized but similar discovery-on-a-budget initiative is GlaxoSmithKline's VPoC--virtual-proof-of-concept--unit.

Many readers will have heard of Eli Lilly & Co.'s Chorus initiative, designed to drive compounds through to proof-of-concept as cheaply and quickly as possible. ( See "Lilly Tries to Buy Time," this issue Also see "Lilly Tries to Buy Time" - In Vivo, 1 December, 2009.and " Lilly's Chorus Experiment," IN VIVO , May 2007 Also see "Lilly's Chorus Experiment" - In Vivo, 1 May, 2007..) Less well-publicized is GlaxoSmithKline PLC's development-on-a-budget initiative, known as the VPoC, or virtual proof-of-concept.

The six-person operation, conceived and run by SVP, Molecular Discovery Allen Oliff, MD, is actually a drug performance unit (DPU), set up 18 months ago at the same time as...

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