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R&D Meets The Crowdscape: BioMed X Looks Outside For Insight

An extended inter-disciplinary approach to preclinical research may offer the best leads against today’s biggest challenges in medicine.

 
• By William Looney

It is a cliché to say that pharma science loves to collaborate – the hard thing is that leaky decision framework by which good ideas do not get executed.

Crowdsource
Crowd science appeals as a remedy for declining productivity in the biopharma pipeline • Source: Gayle Rembold Furbert

Solving hard problems in biopharma usually starts like this: expert teams of specialists develop a research premise, test it in a carefully-defined cohort of patients and then validate the results using standard randomized methodologies. Failure rates are high because, at heart, drug research remains a messy exercise in improvisation. That is because we still do not know the basics of how nature uses physics to make the biology that determines individual health status.

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