Innovation

Podcast: Meet Grace, The Clinical Trial AI Agent

 
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In Vivo spoke with Tran Le and Sohit Gatiganti, co-founders of Grove AI and developers of Grace, a voice-based AI agent to streamline clinical trial processes.

Barcelona Health Hub: Where Digital Health Innovation Meets Historic Art Nouveau

 
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The Barcelona Health Hub is a nonprofit that seeks to advance digital health innovation by bringing together start-ups, investors, health care institutions and corporations.

Aurion Biotech’s Ophthalmic Cell Therapy For The Masses

 
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Aurion Biotech is developing a cell therapy for corneal diseases that is cheap enough to produce and can be scaled that it should reach the masses in a way that other cell therapies cannot.

BPGbio: Fusing Patient-Driven Innovation With Causal AI

 
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Biotech BPGbio applies causal AI to generate insights from samples from what the CEO says is one of the world's largest biobanks. With several promising late-stage programs, its platform seems to be yielding fruit.


20 Voices: What Does 2025 Hold For Biopharma?

 

Twenty executives in the biopharma industry outline their expectations for key trends and developments this year. A selection of commentary from a broad industry survey by Scrip.

Biotech Aims For NET Gains By Targeting Neutrophil Extracellular Traps

 
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Neutrophil Extracellular Traps are a double-edged sword in the immune system, capable of both defending against pathogens and driving inflammatory diseases. Their complex role in health and disease is being approached by innovative researchers and biotechs, who are working to harness their power while mitigating their harmful effects.

Neurodegenerative Disease Investment: Shifting Paradigms Beyond Amyloid And Tau

 
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Companies are exploring new mechanisms of action beyond traditional amyloid and tau and both investors and big pharma are willing to make deals when the science is compelling, panelists at Biotech Showcase said.

Google Co-Authored Report Lays Out Roadmap For AI In Tackling AMR

 
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Close collaboration between industry, academia and government in employing artificial intelligence could solve the looming threat of antimicrobial resistance, a new report co-authored by Google says.


Micron’s Peel & Stick Technology Offers Hope For Needle-Free Drug Administration

 

Steven Damon, Micron Biomedical CEO, discusses the promising future of Micron’s microneedle technology, which allows for painless vaccine delivery through pressing a small patch onto the skin.

Orano Med And Molecular Partners Transform Thorium Into Cancer Therapy

 
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Swiss firm Molecular Partners and French national offshoot Orano Med have partnered to develop a potent new class of radiopharmaceuticals.

Licensing For Innovation: A Decade Of Pharma Product Deals

 

Licensing deals have been growing in popularity over outright acquisitions in the pharmaceutical industry over the past decade. Licensing deals have doubled in number from 2015 to 2024, while M&A activity has decreased post-COVID. We consider the advantages of licensing deals and review notable licensing deals from the past 10 years with the potential to deliver high value relative to their initial investment.

In Search Of Rare Disease Treatments, Nonprofits Can Lead the Charge

 
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Nonprofits are finding new ways to address market gaps and develop treatments for rare diseases with little commercial attraction.


Podcast: Harness Therapeutics CEO Talks Somatic Expansion For Neurodegeneration

 
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Harness Therapeutics' CEO talked to In Vivo about the company's strategy for expansion and partnering in the neurodegeneration space.

Ginkgo Bioworks' LLM Addresses mRNA Stability

 
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Gingko Bioworks has released a large language model designed to improve mRNA stability.

Beyond Biosimilars: Novel Approaches To Treat Wet AMD

 
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Beyond the cost savings of biosimilars, the true evolution in wet AMD treatment is happening by companies developing next-generation therapies that aim to reduce injection burden, introduce novel mechanisms, and potentially alter disease progression.

CCRM: Building A Global Regenerative Medicine Ecosystem From Canadian Roots

 
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The Centre for Commercialization of Regenerative Medicine has spent over a decade crafting a cell and gene therapy ecosystem in Canada. Now it is replicating the model abroad.


From Stem Cells To Organoids: Roche’s Hans Clevers’s Quest To Transform Drug Development

 
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This is Part 1 of a 2-part profile of Hans Clevers, Head of Pharma Research and Early Development at Roche.

Artiva Leverages Unmodified NK Cells To Challenge CAR-T Paradigm

 
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Artiva Biotherapeutics is hoping its NK cell therapy approach, which uses un-engineered cells, will prove effective in both oncologic and autoimmune indications and safe enough to be given in the community setting.

Beyond CPAP: Apnimed’s Potential To Transform Sleep Apnea Management

 
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Boston-area biotech Apnimed expects Phase III readouts for its obstructive sleep apnea combination drug by May. Patients with OSA are desperate for a pill to treat the condition, and GLP-1 agonists are only part of the solution.

Alkermes Wide Awake To Blockbuster Narcolepsy Market Potential

 
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Having spun out its oncology business and put all of its eggs into a neuroscience-shaped basket, how is Alkermes executing on its 2024 stated strategy to return to its CNS roots?