Market Intelligence

BioBytes: AI-Related Deals In Q1 2025

 
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AI-related deal activitiy in the first quarter of 2025 was punctuated by a last-minute $600m raise for Isomorphic Labs.

How Charl Van Zyl Is Reimagining Lundbeck

 
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Lundbeck CEO Charl van Zyl spoke with In Vivo about the Danish company’s multipronged transformation, one that involves a rethink of company culture, pipeline strategy and a sharpened focus on innovation in rare neurological disorders.

Top 12 Pharma Companies: Pfizer Tops The Leaderboard Again

 

The world’s biggest pharmaceutical companies mostly saw growth in 2024 but 2025 promises to be more of a mixed bag with headwinds including losses of exclusivity, Medicare Part D redesign and challenges in the Chinese market.

Regenxbio’s Triple Threat: Partnered Programs, DMD Progress And In-House Manufacturing

 
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Regenxbio is riding a wave these days, with all three of its clinical-stage programs set to reach critical milestones this year and recent positive news on its DMD gene therapy, just as Sarepta suffered a setback with a death related to its DMD treatment. In Vivo spoke with CEO Curran Simpson about the company’s plans and strategic decisions.


Mirum’s Rare Disease Strategy: A Blueprint For Sustainable Growth

 
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From a $7m discarded asset to a $336m commercial portfolio, In Vivo looks inside Mirum Pharma’s disciplined strategy for identifying, acquiring and revitalizing overlooked rare disease programs while building toward billion-dollar potential.

Aurion Biotech’s Ophthalmic Cell Therapy For The Masses

 
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Aurion Biotech is developing a cell therapy for corneal diseases that is cheap enough to produce and can be scaled that it should reach the masses in a way that other cell therapies cannot.

BPGbio: Fusing Patient-Driven Innovation With Causal AI

 
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Biotech BPGbio applies causal AI to generate insights from samples from what the CEO says is one of the world's largest biobanks. With several promising late-stage programs, its platform seems to be yielding fruit.

Q&A: Rentschler’s CEO On The CDMO’s Pivot Away From Cell And Gene Therapy And More

 
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Rentschler Biopharma CEO Benedikt von Braunmühl tells In Vivo about the CDMO's strategic decision to exit the cell and gene therapy manufacturing space.


20 Voices: What Does 2025 Hold For Biopharma?

 

Twenty executives in the biopharma industry outline their expectations for key trends and developments this year. A selection of commentary from a broad industry survey by Scrip.

Orano Med And Molecular Partners Transform Thorium Into Cancer Therapy

 
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Swiss firm Molecular Partners and French national offshoot Orano Med have partnered to develop a potent new class of radiopharmaceuticals.

Hans Clevers' Vision For The Future Of Drug Development And Personalized Medicine

 
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This is the second of a two-part profile of Hans Clevers, head of Pharma Research and Early Development at Roche, in which he talks about his vision for the future of personalized medicine.

Dealmaking Quarterly Statistics, Q4 2024

 
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During Q4, biopharma merger and acquisition deal value reached $9.4bn and drew in $72.8bn in potential deal value from alliances. Device company M&A values reached $395m, while in vitro diagnostics and research tools players’ M&A activity totaled $604m.


In Search Of Rare Disease Treatments, Nonprofits Can Lead the Charge

 
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Nonprofits are finding new ways to address market gaps and develop treatments for rare diseases with little commercial attraction.

Podcast: JPM Tracked And Unpacked

 

In the latest episode of the In Vivo podcast, Citeline’s expert panel of reporters and analysts unpack the biggest deals, trends and innovations following the J.P. Morgan Healthcare Conference.

Medtechs Tell Incoming German Coalition: Elevate POC, Tackle Reimbursement, Drive Digital Change

 
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Improving reimbursement and integrating digital process across health care should be two priorities for the incoming German coalition, says Martin Walger, chief executive of the IVD industry association, the VDGH, in part two of his interview with In Vivo.

Beyond Biosimilars: Novel Approaches To Treat Wet AMD

 
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Beyond the cost savings of biosimilars, the true evolution in wet AMD treatment is happening by companies developing next-generation therapies that aim to reduce injection burden, introduce novel mechanisms, and potentially alter disease progression.


Deals In Depth, January 2025

 
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Ten $1bn+ alliances were penned in January, and two exceeded $2bn.

Financing Quarterly Statistics, Q4 2024

 
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During Q4, biopharmas brought in an aggregate $16.8bn in financing and device company fundraising totaled $2.3bn; while in vitro diagnostic firms and research tools players raised $294m.

German Election 2025: Market Access And EU IVD Regulation In Focus For Medtechs Ahead Of Poll

 
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Lawmaking in Germany came to a halt after the federal election was called, meaning cardiovascular detection and pharmacy legislation were put on hold. In part one of a two-part interview on key themes for industry, Martin Walger, chief executive of the IVDs industry association, the VDGH, lays out the hopes and fears of IVD companies in the run up to the late February vote.

Japan In 2025: Policy Give, Pricing Take Set To Continue

 
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While Japan looks set to further improve policies to support ventures and ease market entry this year, these will contrast with ongoing reimbursement price controls.