Market Intelligence

Only Half Of 2024’s Biggest Launches Belong To Big Pharma

 

Just a handful of big pharma approvals of 2024 are tipped to be multi-billion dollar blockbusters. Even though it is still early days for these drugs, the pull of M&A is looking increasingly strong for big pharma as more smaller firms go it alone.

Global Regulator Action To Improve Diversity In Clinical Trials

 
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As efforts to improve diversity in clinical trials gain momentum globally, regulators in the UK, the EU, Canada, Australia and Japan were asked about their efforts to support representative enrolment. 

2024 Drug Launches Reflect A Breakout Year For Liver Disease

 

The year’s new drugs included the first drug approved for non-alcoholic steatohepatitis (NASH) and two drugs for primary biliary cholangitis (PBC).

Podcast: Pre-JPM Biotech Dealmaking Panel

 
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As we enter 2025, In Vivo convened a group of biotech executives for a wide-ranging conversation about dealmaking this year and the challenges and opportunities for companies in the cardiometabolic, longevity, radiopharmaceuticals and cancer spaces. Essential listening before JPM.


La French Touch: How France Has Built a Reputation for Excellence In Medtech

 

France’s medtech sector is strong, growing and innovative. In Vivo spoke to several French medtech leaders about the unique features and pitfalls their industry may face.

From IPOs To Industrial M&A: The Evolution of China’s Pharmaceutical Dealmaking

 
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In 2023, China emerged as the second largest exporter in the global biopharmaceutical pipeline. While innovation, international expansion, and commercialization remain pivotal, the industry's growth has increasingly relied on industrial efforts due to less active capital markets.

China Dominates APAC’s Emergence As Global Trials Hub

 
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Asia-Pacific continues to solidify its position as a key location for clinical trials, with China in particular dominating such activity in the region, and increasingly globally, a Citeline White Paper shows.

Atopic Dermatitis: A Crowded Field With Room To Grow

 

Topical, oral and biologic drugs have made a difference for patients with atopic dermatitis, but full control remains elusive for many, with the heterogeneous condition, leaving open a door for new medications.


Data: The Clinical Trials Space Rebounds

 
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The complex landscape of clinical trials, fraught with pressures and risks, and exacerbated by the adoption of new technologies, regulatory burdens, and drug pricing negotiations, is rebounding with aplomb.

Circio’s Vision For Long-Lasting Nucleic Acid Therapeutics

 
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Circular RNA has several advantages, but the field is young. Scandinavian startup Circio Holdings believes its version of the technology will prove the most robust.

Navigating The Uncharted Waters Of EU HTA

 
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The EU-level joint clinical assessments that will be introduced under the Health Technology Assessment Regulation from January 2025 represent a huge shift for drug companies launching products in the EU. Industry experts Alexander Natz and Matias Olsen offer key advice to help companies prepare for what is to come.

Failing Fast: New And Strategic Ways To Prune Your Portfolio

 
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AI and machine learning can help companies push failures further up to avoid costly late-stage disappointments.


Medtech Industry Reaches New Chapter In Its Structural Evolution

 
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The Top 100 ranking of global medtechs by revenues for 2023 illustrated how the leaders continue to tailor innovation to users and patients according to market trends while driving portfolio management for growth.

Scrip 100: By The Numbers

 

Despite experiencing significant drops in pharmaceutical revenues in 2023, Pfizer and AbbVie maintained their top positions, ranking first and second respectively, in the latest Scrip 100.

The Scrip 100: Changes At The Top Of The Leaderboard

 

Pfizer continued its reign as the Scrip 100 leader for a third year, while Lilly and Novo climbed higher.

Radiopharmaceutical Strategies Begin To Take Shape As Field Rolls Into 2025

 
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Radioligand therapies offer a resistance-proof mechanism that complements immuno-therapies and other drug classes. No wonder oncology players continue to pile in.


Financial Market Conditions Still Choppy As Rising Tide Has Yet To Lift All Ships

 
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Venture capital funding is up, and initial and follow-on public offerings are growing, but the building wave of investment in biopharma has not reached all companies.

The Good, The Bad, And The Uncertain: Trump’s Second Administration And The Rx Industry

 
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The pharma industry arguably suffered none of the downside risks that were possible during the first Trump administration, and their relationship with Biden could not have gone much worse. And while they may hope a Trump return could help their fortunes, having RFK Jr. supervising the FDA is likely not the prescription they want.

Combos, New MOAs, And Oral Formulations Of Injectables: Lilly’s Immunology Strategy

 
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In a competitive immunology landscape, Eli Lilly is looking for novel agents, oral formulations of injectables, and combination therapies that can optimize response and expand the patient pool.

Generics Industry Hungry For More After Showing Larger GLP-1 Appetite In 2024

 
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GLP-1 drugs like Ozempic and Mounjaro have shaken up pharma, crossing firmly over into the mainstream while netting fortunate suppliers billions of dollars in the process. As patent expiry approaches for first- and second-generation products, generics manufacturers are gearing up to take a share of the spoils.