Market Access

Regenxbio’s Triple Threat: Partnered Programs, DMD Progress And In-House Manufacturing

 
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Regenxbio is riding a wave these days, with all three of its clinical-stage programs set to reach critical milestones this year and recent positive news on its DMD gene therapy, just as Sarepta suffered a setback with a death related to its DMD treatment. In Vivo spoke with CEO Curran Simpson about the company’s plans and strategic decisions.

Therapeutic Or Cosmetic? Patent Strategies For Dual-Use Innovations

 
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In the pharma and cosmetic sectors, innovation often arises from new uses for known compounds. While the compounds may not be patentable, their new applications can be. European law allows patents on substances used in medical methods, but not on the methods themselves.

EU Medtech Heading For Turmoil? Navigating The Impact Of US President Trump’s Orders

 

In the wake of a series of unprecedented executive orders from US President Trump, the EU medtech industry faces significant political, regulatory and business challenges. Swift and strategic action is essential to ensure stability and safeguard patient safety.

Prevention And Deregulation Likely To Be Central In German Coalition’s Healthcare Plan

 
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Germany’s Union parties may have little alternative than to bring the SPD into a new four-year coalition, says Clifford Chance partner and life sciences legal expert Gunnar Sachs. Health policy will likely see both textural and structural changes.


Infographic: Analyzing The Gap In Women’s Health Care

 

Looking at a recent McKinsey report alongside our Evaluate data, the below infographic provides insight into the investment scene of pharma and raises questions as to how the industry is seemingly yet to seize the opportunity in women's health.

In Search Of Rare Disease Treatments, Nonprofits Can Lead the Charge

 
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Nonprofits are finding new ways to address market gaps and develop treatments for rare diseases with little commercial attraction.

Medtechs Tell Incoming German Coalition: Elevate POC, Tackle Reimbursement, Drive Digital Change

 
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Improving reimbursement and integrating digital process across health care should be two priorities for the incoming German coalition, says Martin Walger, chief executive of the IVD industry association, the VDGH, in part two of his interview with In Vivo.

German Election 2025: Market Access And EU IVD Regulation In Focus For Medtechs Ahead Of Poll

 
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Lawmaking in Germany came to a halt after the federal election was called, meaning cardiovascular detection and pharmacy legislation were put on hold. In part one of a two-part interview on key themes for industry, Martin Walger, chief executive of the IVDs industry association, the VDGH, lays out the hopes and fears of IVD companies in the run up to the late February vote.


Takeda Breathes New Life Into Entyvio With Preventative Use In Crohn’s Disease

 
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Takeda’s head of gastroenterology talked to In Vivo about the major’s plans for finding biomarkers for Crohn’s disease as part of a Euro-wide prevention and interception trial.

Growing Calls For Labelling Changes With Obesity Patients In Mind

 
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Despite significant investments in weight loss treatments, pharmaceutical companies face criticism for neglecting to study their drugs in obese patients, possibly leading to incomplete labeling and patient risks, prompting calls for the FDA to enforce more inclusive clinical trials and updated drug information.

Medtech Radar 2025: EU’s MDR Woes – Paying The Price For ‘Fixing It When It Ain’t Even Broke’

 
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ZS principal Brian Chapman tells In Vivo what is troubling the global medtech industry at the turn of 2025, and takes the opportunity to chide the EU for its persistent fixation on taking on the “problem that did not need to be solved.”

Innovation And Accessibility: India’s Advanced Therapy Pricing Challenge

 
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As India prepares to commercialize its first advanced therapies it must engage key stakeholders to ensure successful implementation. Learning from global best practices and managing pricing strategies will be crucial to maximize access, deliver high-quality outcomes, and sustain innovation through reinvestment in R&D.


Finding The Balance: First-In-Class Versus Best-In-Class

 
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As pharmaceutical companies face a crowded and competitive landscape, the debate between being first-in-class or best-in-class is evergreen. This strategic choice impacts new product launches, with first-to-market therapies offering market share and brand recognition advantages, while best-in-class options can capture value through product differentiation and commercial execution. In Vivo talked to L.E.K. Consulting on how to make a product stand out from the crowd.

Opinion: AI Use In Rebate Management

 
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Pharmaceutical manufacturers face unique challenges, particularly when it comes to managing thousands of complex rebate contracts and connecting the dots between contract agreements and business performance.

Amgen’s Surprise Aflibercept Launch Shakes Up US Biosimilars In 2024

 
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As the US biosimilars market approaches the end of its first decade, it has seen another busy year, with Amgen’s surprise launch of a rival to Eylea shaking up expectations as other first-time approvals rolled in throughout 2024. Meanwhile, competition to Stelara is waiting in the wings from the start of 2025.

The Good, The Bad, And The Uncertain: Trump’s Second Administration And The Rx Industry

 
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The pharma industry arguably suffered none of the downside risks that were possible during the first Trump administration, and their relationship with Biden could not have gone much worse. And while they may hope a Trump return could help their fortunes, having RFK Jr. supervising the FDA is likely not the prescription they want.


Is The EU Recreating A Different Monster Of A Regulatory Labyrinth?

 

Reflecting on 40 years of EU medtech regulation makes me realize how incredibly far we have come. But have we come full circle and replaced the frustrations of four decades ago with a different, but equally challenging, set of problems?

US Drug Pricing And Reimbursement Trends 2025

 
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As the pharmaceutical industry readies itself to navigate the complexities of 2025, US pricing trends reveal a landscape shaped by regulatory and legislative changes, innovative pricing models, and the ongoing impact of inflation.

Uncertainty Remains Over The Future Of Regulatory Data Protection In The EU

 
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As talks continue on the EU pharmaceutical legislative reform proposals, drug firms may have to wait some time before they find out what the future periods of regulatory data protection and orphan market exclusivity will be.

Korea Lays Out Roadmap For Use Of AI Across Drug Development

 
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The five-year roadmap aims to expand support for AI research and development in essential health care and new drug development, as well as advance medical data usage systems and enable its safe use.