Business Strategy

Oncology’s Next Decade: The Therapies And Players Reshaping A $400bn Future

 

Launching In Vivo’s oncology therapeutic review series, this first instalment provides a data-led primer on the global cancer landscape. Future instalments will explore market dynamics, pipeline evolution and the innovations set to define oncology therapeutics through 2032.

Chugai’s Narrow Partnering Strategy Means Less Competition

 
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Chugai’s partnering office in South San Francisco advances the Japanese company’s business development activities in the US beyond its venture fund established in Boston in 2023.

Adapt To Survive: Private Hospitals In A High-Pressure Landscape

 
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Payers' and patients' growing preference for outpatient care is increasing pressure on private providers to continually reassess how they deliver value. Jean-Philippe Grosmaitre and Guillaume Duparc, partners at L.E.K. Consulting, outlined growth opportunities available to private hospitals.

The Autonomous Lab: Part 2

 
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In this two-part series, In Vivo examines who is building the autonomous lab, what architectural and business model choices they are making, and what the implications are for drug discovery organizations, external R&D partnerships and the workforce that will be asked to operate these systems.


Excited About AI, Skeptical Of The Price Tag: Seed Investors Sound Off

 
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Seed investors are enthusiastic about AI in drug discovery but skeptical of the valuations it is used to justify. At a recent panel, they drew a sharp line between real capability and an “AI veneer.”

‘The Pirates All Know Where The Treasure Is’ – Staying Ahead Of The Competition In US Biosimilars

 
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At the AAM’s Access! 2026 conference, a dedicated panel on the latest developments for biosimilars discussed challenges and opportunities in the US market, predicting consolidation among current players as well as calling for policies that put biosimilars first.

Merck’s Oncology Portfolio Strategy Beyond Keytruda

 
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Merck's post-Keytruda oncology strategy rests on three pillars – immune deepening, tissue targeting and tumor-intrinsic mechanisms – anchored by patient selection, AI-accelerated discovery and a KRAS bet that could define its next era.

The Autonomous Lab: Part 1

 
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In this two-part series, In Vivo examines who is building the autonomous lab, what architectural and business model choices they are making, and what the implications are for drug discovery organizations, external R&D partnerships and the workforce that will be asked to operate these systems.


Why ‘Platform Or Perish’ Is Cell Therapy’s New Reality

 
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Something fundamental has shifted in cell therapy investment over the past 18 months. No longer about which science works, it has evolved around the question of which business model pharma believes it can scale. Increasingly, that question is being answered before a single patient is enrolled.

Aqemia Bets Physics, Not Data, Is The Key To Novel Drug Discovery

 
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Aqemia uses proprietary physics-based solvers paired with generative AI to discover genuinely novel drug candidates, bypassing historical training data to crack targets others cannot.

Praxis Eyes Blockbuster Future As Precision Neurology Pipeline Matures

 

Praxis Precision Medicines is planning to shift from a clinical-stage company to a competitive commercial player in CNS, with the potential to launch multiple blockbuster medicines in the near future.

How Asia’s Biopharma Transformation Is Reshaping Global Deal Flow

 
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A decade ago, China was buying Western drugs. Now it is selling them. Executives who ignore the shift do so at their peril.


Pressure, Pivot And The Promise Of AI: BCG Maps Biopharma’s Defining Challenges For 2026

 
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Recent BCG reports and interviews reveal an industry under pressure and racing to adapt through AI, new deal structures and direct-to-patient models.

Big Promises, Long Timelines – Trump’s US Pharma Investment Push

 

While investment promises appear to be in billions of dollars, industry experts remain skeptical.

Burn Control And Subcutaneous Focus: OSE’s Bid To Reprice Its Science

 
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When OSE Immunotherapeutics' board ousted CEO Nicolas Poirier in October 2025, it handed his successor a clear mandate: spend less, partner sooner and stop asking shareholders to wait.

Biopharma Deal Making In 2026: Confidence Returns, But On New Terms

 
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Executives from Novo Nordisk, Ipsen, Astellas, Acadia and Flagship Pioneering agree: the dealmaking environment is improving but the calculus has changed. Flexible structures, sharper therapeutic focus, and the long shadow of patent cliffs and pricing policy are reshaping how partnerships get done.


BioBytes: BMS Taps Evinova’s AI Platform To Optimize Global Portfolio

 
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Bristol Myers Squibb will deploy Evinova's AI-native platform across its global clinical portfolio to optimize trial design, reduce costs, and accelerate development timelines.

Immunis Bets Longevity Medicine Needs a Business Model, Not Just Biology

 
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Immunis's secretome therapy showed 26% gait speed improvement in sarcopenic seniors, validating a longevity platform that sidesteps FDA's refusal to recognize aging as disease.

From CF To Big Pulmonary Markets: SpliSense’s Strategy To Make Inhaled RNA Work

 
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SpliSense is the first company to show inhaled antisense oligos improve lung function in cystic fibrosis, validating its platform for larger COPD and asthma markets.

Biogen’s Alisha Alaimo On The Company’s Next Big Commercial Build

 

Biogen’s president and head of North America talked to Scrip about the company’s commercial expansion into new areas in immunology and nephrology.