Generics Industry Hungry For More After Showing Larger GLP-1 Appetite In 2024

 
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GLP-1 drugs like Ozempic and Mounjaro have shaken up pharma, crossing firmly over into the mainstream while netting fortunate suppliers billions of dollars in the process. As patent expiry approaches for first- and second-generation products, generics manufacturers are gearing up to take a share of the spoils.

Deals In Depth: October 2024

 
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Ten $1bn+ alliances were penned in October, and three exceeded $2bn.

US Drug Pricing And Reimbursement Trends 2025

 
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As the pharmaceutical industry readies itself to navigate the complexities of 2025, US pricing trends reveal a landscape shaped by regulatory and legislative changes, innovative pricing models, and the ongoing impact of inflation.


Commercialization 3.0: Achieving New Product Success In Health Care’s New Era

 
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Despite the importance of developing and commercializing new products to fuel pharma revenue growth, it is estimated that approximately up to 50% of drug launches fail to meet financial expectations. We explore how to maximize product success in pharma's value era.

China Makes Its Presence Felt In Asia 100 Sales

 
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While Japanese firms still dominate the money spinners in Asia, companies from China and, lesser so, India are starting to stand out from the crowd.

A Familiar Leading Pack Conceals Changes For Off-Patent Industry Leaders

 
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Our latest ranking of the world’s leading off-patent companies reflects a fairly stable leading group this year – but this belies the significant evolutions seen for major generics and biosimilars players over the past 12 months.

Winning With Partnerships: How To Turn A Three-Decade-Old Biotech Profitable

 
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Since taking on the CEO role at Theratechnologies in 2020, Paul Lévesque has made it his priority to beef up the company’s commercial portfolio and look for partnerships on potentially high-value programs. Now, the Canadian biotech is turning a profit for the first time in many years.


Big Biotech’s ROI Overshadowed By Big Pharma But Exceptions Exist

 

While big pharma has significantly higher R&D and acquisition expenditures, certain biotechs have outperformed in terms of ROI and have substantial potential for future growth with their strong pipeline assets.

Deals In Depth: September 2024

 
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Three $1bn+ alliances were penned in September.

Schrödinger’s Akinsanya On Low-Risk Pipeline Growth And Platform Evolution

 
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Schrödinger has for years discovered drug candidates for other companies and derisked them, testing them in silico using its computational models. Now, it is exploring its own ability to develop drugs in the clinic, starting with low-risk bets. Will the company’s approach succeed where others have failed?

Deals Shaping The Industry, September 2024

An interactive look at pharma, medtech and diagnostics deals made during August 2024. Data courtesy of Biomedtracker.


The Anatomy Of Astellas And Poseida's CAR-T Deal

 
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Dealmakers from CAR-T biotech Poseida Therapeutics and Astellas recently sat down with In Vivo to discuss how they reached a $600m deal that combines their technologies and how they plan on moving forward.

Bristol Myers Squibb ASPIREs For Access In LMICs

 

BMS has launched a new cancer drug access program for low-to-middle income countries, focusing on addressing health inequities and widening accessibility.

Fusion CEO Talks AZ Deal Making And Canada’s Blossoming Biotech Ecosystem

 
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Fusion Pharmaceuticals Inc CEO John Valliant talked to In Vivo about Canadian leadership in radiopharmaceutical innovation, its differentiated approach, and excitement around combination therapies for precision cancer treatments.

Moderately Optimistic: Rounding Out Deal Making In 2024

 
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Dealmaking trends in 2024 point toward a healthier financial ecosystem than in 2023. However, with a challenging three quarters in 2024, enthusiasm should be curbed as 2024 rounds out in a slow and steady manner.


Biopharma Dealmaking: All About The Science And Personal Chemistry

 

Business development leaders from AstraZeneca and Novartis and a biotech CEO get frank about what they want from the other side, highlighting the need for transparency during competitive negotiations, plus a shared spark of enthusiasm about pursuing novel science.

Pharma’s Future: More Development With Less Dollars

 
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Profit warnings from CDMOs ring a warning bell that pharma is cutting its early research spend. What impact will spending controls and the tsunami of AI have on the pharmaceutical industry's R&D investments?   

2025’s Therapy Area Growth Drivers And Brakes: Part Three

 

The final instalment of In Vivo’s three-part series delves into the therapeutic categories that will propel forecast pharmaceutical sales growth for 2025, focusing on mood disorders, immunodeficiency, viral infections, and blood cell disorders.

US Approvals Of Novel Drugs Set To Hit 10-Year High In 2025

 

But 2024 will see a lull between two strong years.