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The Value And Challenge Of Focus In Pharma

 
• By Josh Hattem

A 10-year review of the top 20 biopharmaceutical companies by revenue found that portfolio focus, not therapeutic area diversity, delivered the strongest growth rates.

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In 2019, the pharmaceuticals industry invested more than half a trillion dollars in M&A and R&D combined. These “bets” are often expensive and speculative: it typically costs $1bn to develop a new drug, with only a 6.9% chance of getting from Phase I development to FDA approval in the US.

A small minority of products that get marketing authorization cross the “blockbuster” $1bn sales threshold in their peak year. This...

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