Pfizer Inc. agreed to pay $43bn in cash for antibody-drug conjugate (ADC) developer Seagen Inc. earlier this month. The US pharma giant said Seagen’s four approved products – three ADCs and a small molecule cancer drug – plus candidates in its pipeline should generate $10bn in annual revenue by 2030. This puts Pfizer less than $5bn away from achieving its goal of adding $25bn in new revenue by 2030 through business development activities.
That level of investment is needed to offset losses of exclusivity (LOEs) later in this decade for multiple blockbuster products, including the CDK4/6 inhibitor Ibrance (palbociclib) for breast cancer
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