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Plagued By Controversy, Promising Alzheimer's Treatment, 2024 To Be Pivotal For Cassava Sciences

 
• By David Wild

All eyes will be on Cassava Sciences in 2024, as it completes two Phase III trials of its closely watched Alzheimer’s disease candidate, simufilam. The drug has been the subject of both skepticism and enthusiasm. 

Cassava Sciences's Phase III Results Will Be Closely Watched In The Year Ahead • Source: Shutterstock

The moment of truth may be approaching for the sometimes-beleaguered pharma company Cassava Sciences. It has moved forward with two Phase III studies of its Alzheimer’s disease candidate, simufilam, enrolling numbers well beyond the target initially set, and one of several investigations into company research has been paused after equivocal conclusions were released in a leaked draft report. 

But with a history of mixed study findings and questions previously raised around data integrity, it is

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