Regenerating Interest In Novel Drugs For Postmenopausal Osteoporosis

New bone-targeted agents for osteoporosis must clear significant obstacles to succeed in a highly generic market, but safety concerns with established agents like bisphosphonates and calcitonin offer a foothold. Phase III anabolic candidates from Amgen and Radius Health aim to build new bone, the holy grail of osteoporosis treatment, but R&D in new anti-resorptive mechanisms to halt bone breakdown also continues.

The fractures that continue to weaken the foundation for currently marketed postmenopausal osteoporosis drugs offer a foothold to sponsors of new bone-building or bone-strengthening agents – but they’ll need to provide data sufficiently compelling to win over insurers who already have a wide choice of low-cost generic options.

Major Phase III programs are underway for new mechanisms to treat osteoporosis, including the partnership of Amgen Inc. and UCB Group, as well as Merck & Co. Inc., even though postmenopausal osteoporosis is considered a forbidding market to enter thanks to the wide range of generic drug therapies on offer

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Pink Sheet for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required

More from Clinical Trials

More from R&D