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Lingering Leqembi Question: When Should Treatment Stop?

 
• By Derrick Gingery

Several questions about the anti-amyloid product used to treat Alzheimer’s remain, which could affirm calls for more US FDA, CMS and NIH collaboration on research.

Alzheimer's puzzle
Neurology professor Randall Bateman said Alzheimer's disease treatment could be managed similar to cancer. • Source: Shutterstock

Even with apparent indicators of efficacy, clinicians still have questions about using Biogen, Inc. and Eisai Co., Ltd.’s Leqembi (lecanimab-irmb) in Alzheimer’s disease patients. Many likely require more study and some could be limiting uptake.

Leqembi has no guidance on when treatment should end, Erik Musiek, an associate neurology professor at Washington University School of...

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Sarepta Refuses To Stop Elevidys Shipments After Third Death Linked To Gene Therapy Vector

 
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CAR-T REMS Removal Should Boost Access, But Long-Term Follow-Up, Black Box Remain

 
• By Sarah Karlin-Smith

The REMS removal and labeling changes should open up CAR-T treatment to many more US patients, although other regulatory hurdles and safety language that experts had wanted removed still stand.

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