The European Pharmacopoeia is abolishing the use of the traditional rabbit pyrogen test (RPT), in a move described as a major achievement for animal welfare and the advancement of modern in vitro approaches, and which will send out a strong message globally.
In Vitro Triumph: European Pharmacopoeia Abolishes Rabbit Pyrogen Test
The use of the RPT is to no longer be required in any text of the European Pharmacopoeia and medicine developers will have to select a suitable in vitro test to control the pyrogenicity of their product.
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